Mar 1, 2019
Our cells, like our homes, fill up with garbage very fast. The latest research from Harvard Medical School reveals that vigorous exercise and even some fasting will help our cells with their housekeeping duties of removing damaged, toxic, and unnecessary proteins.
Previous studies have shown that the signal for flushing your cells is the messenger molecule cyclic-AMP. This new discovery that exercise triggers the dumping junk proteins from the cell is almost certainly explained by that fact that exercise bumps up your adrenalin and that, in turn, triggers a burst of cyclic-AMP.
Since cell garbage plays a key role in neurodegenerative diseases such as Alzheimer’s and Parkinson’s as well as storage diseases like amyloidosis, it may well be that prevention of these dread diseases can be added to the list of exercise’s benefits.
#exercise #cellcleansing #cAMP #Alzheimers #Parkinsons #healthnews
Jordan J. S. VerPlank, Sudarsanareddy Lokireddy, Jinghui Zhao, Alfred L. Goldberg. 26S Proteasomes are rapidly activated by diverse hormones and physiological states that raise cAMP and cause Rpn6 phosphorylation. Proceedings of the National Academy of Sciences, 2019; 201809254 DOI: 10.1073/pnas.1809254116