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Howard G. Smith, M.D. is a former radio medical editor and talk show host in the Boston Metro area.  His "Medical Minute" of health and wellness news and commentary was a regular weekday feature on WBZ-AM, WRKO-AM, and WMRE-AM.   His popular two-way talk show, Dr. Howard Smith OnCall, was regularly heard Sunday morning and middays on WBZ.

Trained at Harvard Medical School and a long-time faculty member at Boston Children’s Hospital, he practiced Pediatric Otolaryngology for 40 years in Boston, Southern California, and in central Connecticut.

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Please note that the news, views, commentary, and opinions that Dr. Smith provides are for informational purposes only.  Any changes that you or members of your family contemplate making to lifestyle, diet, medications, or medical therapy should always be discussed beforehand with personal physicians who have been supervising your care.

Aug 2, 2019



A new study from The University of Buffalo’s pharmacology department suggests that a glass of red wine may contain not one but two calming ingredients that control sress.  We all know about the alcohol, but adding to its effect is the plant compound resveratrol that’s found in the skin and seeds of the grape.


The resveratrol works to relieve stress and depressive feelings by opposing the “downer” psychological effects of corticosteroids, the fight or flight hormones.  This effect might be able to help persons with severe anxiety and depressive disorders who fail to respond to many current medications that rely on modulating the brain’s serotonin- and noradrenaline- controlled functions.


Since the alcohol in red wine can be a problem for some, a handful of good old red grapes, with seeds or seedless, might just be THE snack to help elevate your spirits at the end of a long day.


Xia Zhu, Wenhua Li, Yongkun Li, Wenhua Xu, Yirong Yuan, Victor Zheng, Hanting Zhang, James M. O'Donnell, Ying Xu, Xiaoxing Yin. The antidepressant- and anxiolytic-like effects of resveratrol: Involvement of phosphodiesterase-4D inhibition. Neuropharmacology, 2019; 153: 20 DOI: 10.1016/j.neuropharm.2019.04.022


#Wine #redwine #resveratrol #anxiety #depression