Aug 2, 2019
When you exercise for stronger muscles and increase your numbers of muscle strength fibers, you produce a neurotransmitter called Brain-Derived Neurotrophic Factor or BDNF. This messenger then drives atrophy of your endurance muscle fibers.
This Yin-Yang relationship is newly described in a study from Switzerland’s University of Basel. This BDNF chemical is produced by the muscle itself in response to strengthening exercises. It triggers remodeling of muscle from slow-twitch endurance fibers into fast-twitch strength fibers.
The investigators also showed that lower levels of BDNF in the muscles of seniors was associated with less decline of muscle bulk with aging. That would suggest strength training is contraindicated for our elders.
Julien Delezie, Martin Weihrauch, Geraldine Maier, Rocío Tejero, Daniel J. Ham, Jonathan F. Gill, Bettina Karrer-Cardel, Markus A. Rüegg, Lucía Tabares, Christoph Handschin. BDNF is a mediator of glycolytic fiber-type specification in mouse skeletal muscle. Proceedings of the National Academy of Sciences, 2019; 201900544 DOI: 10.1073/pnas.1900544116
#Strength #endurance #BDNF #muscleatrophy