Oct 30, 2021
Let’s look at the latest CDC guidelines regarding who should receive booster doses.
Who needs a booster shot?
A 3rd shot should be given as a booster for those who received complete vaccination with an mRNA vaccine, either Moderna or Pfizer, at least 6 months earlier and;
A 2nd shot as a booster should be given to all those who received complete vaccination with the
Johnson & Johnson-Janssen vaccine at least 2 months earlier. That’s it. Any of the vaccines may be used.
Immunocompromised persons more than 28 days following initial vaccination with either Moderna or Pfizer should immediately receive a 3rd shot consisting of a full 100 ug dose of Moderna or a 30 ug dose of Pfizer.
Which booster shot to receive?
Clinical trials show that each booster shot including a full dose of Pfizer, a half dose of Moderna, or a full dose of the J&J significantly increases anti-CoVid immunity as measured by antibody levels. One study of mix and match strategies showed that both work and any of the vaccines would produce the same or higher level of anti-CoVid immunity.
Discuss your options with your provider. Each vaccine has slight associated risks for the booster as they did for the initial vaccination: Pfizer and Moderna - myocarditis more frequent in men and younger adults; J&J - thrombosis with platelet depletion for women 18-49 and Guillain-Barré syndrome for men 50-64. If you are in these groups, the CDC recommends consideration of an mRNA booster with Moderna or Pfizer.
The CDC just added several recommendations for those moderately or severely immunocompromised. Those 6 months or more after their 3rd shot or booster should consider a 4th shot or 2nd booster.
These are the CDC booster guidelines as of October 26, 2021.
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